Minimum effective dose vs LD50 for training

This is going to be one of my shorter blogs, but hopefully just as thought provoking. First a copy and paste on minimum effective dose (MED) from wikipedia:

An effective dose (ED) in pharmacology is the dose or amount of drug that produces a therapeutic response or desired effect in some fraction of the subjects taking it.The importance of determining the therapeutic range of a drug cannot be overstated. This is generally defined by the range between the minimum effective dose (MED) and the maximum tolerated dose (MTD).

If we also define the LD-50 as:

In toxicology, the median lethal dose, LD50 (abbreviation for “lethal dose, 50%”), LC50 (lethal concentration, 50%) or LCt50 (lethal concentration & time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.

Now, if we look at these regarding training. MED would be the minimum amount we can do and still see improvements. MTD would be the maximum amount of training a particular athlete can take before breaking. If MTD is less than current training, you have an injured athlete. LD50 is the point where half of the athletes in your group are injured.

Count how many and how often the athletes you coach are injured and decide where on the continuum your program lies. How many have been given a lethal dose of training.

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